CRISPRgenee is a new method that combines gene silencing and cutting to improve loss-of-function studies in human cells.

Researchers engineered and screened dozens of base editors to precisely target a single mutation without editing other portions of the DNA.

When scientists discovered how bacteria protect themselves against viral invaders, called phages, in the early 2000s, little ...

Cas9 is directed to its target within the DNA sequence through the use of the guide RNA. A specific sequence of DNA that is between two and five nucleotides in length must align with the 3’ end of the ...

The new system developed by Professor Chad Mirkin delivers CRISPR machinery more safely and effectively into cells.

Horses with genomic edits to make them run faster have been banned from polo, but a zoo of CRISPR-edited animals is gaining ...

Multisystemic smooth muscle dysfunction syndrome (MSMDS) is a rare condition associated with stroke, aortic dissection ...

Scientists study a molecular machine that moves jumping genes in DNA, paving the way for a new gene editing tool beyond ...

This story is part of a series on the current progression in Regenerative Medicine. This piece is part of a series dedicated to the eye and improvements in restoring vision. In 1999, I defined ...