Researchers engineered and screened dozens of base editors to precisely target a single mutation without editing other portions of the DNA.

A research team has established a CRISPR/Cas9 gene-editing system for Chrysanthemum morifolium, targeting the CmPDS gene to explore gene functions and enhance breeding. By combining transient and ...

When scientists discovered how bacteria protect themselves against viral invaders, called phages, in the early 2000s, little ...

Multisystemic smooth muscle dysfunction syndrome (MSMDS) is a rare condition associated with stroke, aortic dissection (tearing) and death in childhood. Currently, there is no effective treatment or ...

More than a decade ago, scientists harnessed a bacterial molecular machine that identifies and cuts specific sections of DNA, ...

Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated (Cas) proteins are core components of fast-evolving therapeutic gene editing tools. Scientists have used CRISPR ...

Like the human immune system, bacteria learn from past infections. CRISPR sequences—short snippets of DNA from previous viruses—guide destructive enzymes towards invading bacteriophages that express ...

Scientists study a molecular machine that moves jumping genes in DNA, paving the way for a new gene editing tool beyond ...

This story is part of a series on the current progression in Regenerative Medicine. This piece is part of a series dedicated to the eye and improvements in restoring vision. In 1999, I defined ...

Immunotherapeutic strategies have made huge strides in cancer treatment for many solid tumors over the past decade. But the promising results have failed to make a large change in the treatment of ...