To investigate the potential role of BMCs in this process, the researchers studied adenovirus, a nuclear-replicating DNA virus. Because the adenovirus proteins involved in genome replication are ...

To replicate, viruses need to make multiple copies of their genome. Almost all encode a protein that does this for them. Hepatitis D virus doesn't. How does it replicate?

Northwestern Medicine scientists have discovered how a common virus linked to birth defects and chronic illness manipulates ...

Researchers from the University of Hong Kong have discovered that the Epstein-Barr virus (EBV), a common human virus closely ...

Published today in the journal PNAS, the study sheds light on the fundamental question of how viruses override their host cells' carefully regulated DNA replicating system to make hundreds of new ...

Because the adenovirus proteins involved in genome replication are distinct from those involved in particle assembly and genome packaging, the researchers reasoned focusing on this virus would ...

Researchers have shown for the first time how Merkel cell polyomavirus (MCV), which causes an aggressive skin cancer called Merkel cell carcinoma, initiates DNA replication in host cells.

Some viruses come and go after making us sick, but some have become a part of us, passed down by our ancestors. San Diego ...

Additionally, targeting a host protein reduces the risk of antiviral resistance. While the study provides important insights into BKPyV replication, the revelation that TAg does not induce cellular ...

However, little is known about how genome replication, particle assembly, and genome packaging are coordinated in the crowded nuclear environment.