An overview of miRNA biogenesis and function in Arabidopsis miRNAs are transcribed from a gene and processed by DCL1, SE and HYL1 into an RNA duplex (miRNA/miRNA*).

Critical for understanding how any miRNA functions is identifying the set of mRNA targets to which it binds in a specific biological context, and also determining how these interactions regulate ...

In mapping miRNA targets, the research team examined the function of the genome of C. elegans, the first animal species whose genome was completely sequenced and a model organism to study how ...

To better understand the function of miRNAs in the pathogenesis of type 2 diabetes, the study detailed the genetic regulation of HPI miRNA expression.

Therefore, DICER cleavage controls miRNA expression and sequences, and thus its cleavage impacts miRNA functions.

They found that A-to-I editing was separate from the miRNA function, and therefore did not modulate it in any functionally important regard.