Researchers have described a large set of previously unrecognized enzymatic domains—named the Lipocone superfamily—and outlined their evolutionary pathway from bacterial defense molecules to key ...

They also transport miRNAs that affect the Wnt signaling components, influencing tumor behavior. Role of Wnt Signaling in HCC Pathogenesis The Wnt/β-catenin pathway is essential for HCC development.

Role of Wnt signaling in HCC pathogenesis The Wnt/β-catenin pathway is essential for HCC development. Its activation promotes hepatocyte proliferation, inhibits apoptosis, and enhances tumor cell ...

Glioblastoma (GBM) is an aggressive form of brain tumor with a poor prognosis. Despite advances in neurosurgery, chemotherapy ...

The molecule Wnt, which plays a role in cell communication during human development, evolved from a superfamily with a shared lipid-modifying mechanism originally involved in bacterial defence and ...