Week 2 of the 2025 college football season begins Saturday with a handful of intriguing matchups in the early window, and the main event -- which happens to be the only ranked-on-ranked game of the entire weekend -- coming later in the day.

Here’s your look at the complete Week 2 college football schedule for today, and the updated live scores brought to you by Sports Illustrated. Sat., Sept. 6 | 12 p.m. | BTN Line: Penn State -41.5

The Washington Mystics lost to the Indiana Fever on Sunday in Baltimore, 94-65. It was their last home game of the season. Washington got walloped in this game from turnovers. They committed 22 of them,

The Louisville Cardinals hosted the James Madison Dukes in a Week 2 college football game. Look back at our UofL football score updates and highlights

The Kentucky Wildcats faced the Ole Miss Rebels in a Week 2 college football SEC game in Lexington. Our highlights from the Kentucky football game:

Three things to watch, two bold predictions and a final score prediction for No. 13 Michigan's marquee matchup with No. 24 Oklahoma in Week 2

Minnesota's dominant showing where eight players scored first-half touchdowns and 10 backs saw carries brought Northwestern State crashing back down to earth after snapping a 20-game losing streak in Week 1.

In the season-opening edition of "Sunday Night Football," the Buffalo Bills play host to the Baltimore Ravens. Heading into this season, the Ravens and Bills look once again like two of the top teams not just in the AFC, but the entire league. Baltimore entered the season tied for the league's best Super Bowl odds, while Buffalo checked in third.